Deadline: January 15, 2026
Award Amount: Up to $1,000,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Nonprofits, and Businesses
Description: The CyberTraining program aims to prepare, nurture, and grow the national scientific research workforce for creating, utilizing, and supporting advanced cyberinfrastructure (CI) to enable and potentially transform fundamental science and engineering (S&E) research and education. The program seeks to ensure broad adoption of CI tools, methods, and resources by the research community to catalyze major research advances and to enhance researchers’ abilities to lead the development of new CI.

Deadline: January 15, 2026
Award Amount: $500,000 to $7,500,000
Match: None
Eligible Entities: Tribal
Description: Offers competitive funding to eligible IHBG formula recipients, namely federally recognized tribes and Tribally Designated Housing Entities (TDHEs), to support affordable housing activities that primarily benefit low-income Native American families. The program prioritizes new construction of housing units, while also allowing rehabilitation, acquisition, and associated infrastructure projects.

Deadline: January 15, 2026
Award Amount: Unspecified; total grant funding $500,000,000
Match: Yes; unspecified.
Eligible Entities: Tribal
Description: Fiscal Year 2024 Flood Mitigation Assistance (FMA) Swift Current aims to better align the delivery of FMA flood mitigation funding to the disaster survivor experience. The purpose of FMA Swift Current is to reduce or eliminate the flood risk to NFIP-participating communities and repetitive flood damage to structures and buildings insured by the NFIP following a flood-related disaster event, and to enhance community flood resilience within NFIP- participating communities. It does so by providing funding for mitigation opportunities immediately after a flood disaster event with the aim of delivering mitigation outcomes.

Deadline: January 15, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: Tribal
Description: Supports federally recognized Tribes in improving transportation safety through plans, data analysis, roadway countermeasures, and infrastructure projects.

Deadline: January 15, 2026
Award Amount: Up to $325,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments and Film/Media
Description: This grant supports the National Digital Newspaper Program, which funds the development of a comprehensive digital archive of historic American newspapers. It encourages collaboration between state-level programs and the Library of Congress to enhance public access to newspaper holdings. Projects are intended to preserve and make searchable a diverse body of historical news publications.

Deadline: January 20, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Education, and Businesses
Description: This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS).

Deadline: January 20, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Education, Nonprofits, and Businesses
Description: This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS).

This FOA seeks exceptionally creative approaches to address major challenges associated with recording and modulating CNS activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain.

Deadline: January 21, 2026
Award Amount: Up to $75,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Education, and Nonprofits
Description: This program aims to prevent and reduce the use of opioids, methamphetamines, and the misuse of prescription drugs among youth aged 12–18. It supports initiatives that provide education, outreach, and intervention strategies to address substance use and promote healthy behaviors. The focus is on implementing evidence-based practices that engage youth and communities in prevention efforts.

Deadline: January 27, 2026
Award Amount: Up to $250,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Nonprofits, Education, and Businesses
Description: Support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. Specifically, this FOA will support the development of exportable training modules designed to enhance training of the biomedical research workforce. Responsive topics will be indicated through Notices of Special Interest released annually by NIGMS.

Deadline: March 1, 2026
Award Amount: Up to $10,000
Match: None
Eligible Entities: Nonprofits and State, City, Township, County or Tribal Governments
Description: Supports nonprofit organizations and local riding clubs in their efforts to promote safe and responsible off-road recreation. The program provides funding for trail development and maintenance, safety education initiatives, and environmental stewardship projects.

Deadline: March 5, 2026
Award Amount: Up to $250,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Education, Nonprofits, and Businesses
Description: This funding opportunity focuses on biomedical discovery and data-powered health, integrating streams of complex and interconnected research outputs that can be translated into scientific insights, clinical care, public health practices, and personal wellness to ensure the research is scalable, reproducible, and generalizable.

The scope of NLM’s interest in these research domains is broad, with emphasis on new and innovative methods and approaches to foster data driven discovery in the biomedical and clinical health sciences as well as domain-independent, scalable, and reusable approaches to discovery, curation, analysis, organization, and management of health-related data and digital objects.

Deadline: March 6, 2026
Award Amount: Up to $100,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Education, Nonprofits, and Businesses
Description: The New Investigator Gateway Award in T1D Research is designed to support a robust pipeline of innovative projects and talented new investigators in T1D research. In addition to providing support for preliminary research, the Gateway program provides an opportunity for new Program Directors/Principal Investigators (PD/PIs) to pursue their studies within the intellectual environment of a select number of large, ongoing collaborative research programs.

Deadline: March 16, 2026
Award Amount: Up to $100,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Nonprofits, and Education
Description: This Small Research Grant will support meritorious projects to provide needed scientific insight to improve the prevention, diagnosis, treatment, and/or care for individuals with Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD). Specifically, this NOFO will support projects covering a wide range of topics related to AD/ADRD. The overall goal of this NOFO is (1) to encourage the next generation of researchers to pursue research and academic careers in AD/ADRD research; and (2) to stimulate established researchers who have not had a major award in AD/ADRD research to perform pilot studies to develop new, innovative AD/ADRD research programs that leverage and build upon their existing expertise.

Deadline: April 14, 2026
Award Amount: Up to $125,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits
Description: Supports community-based efforts to prevent and reduce youth substance use, including alcohol, tobacco, and illicit drugs. It provides funding for coalitions that engage multiple sectors, such as schools, law enforcement, and local organizations, to implement evidence-based prevention strategies. The initiative aims to strengthen community capacity and promote sustainable, data-driven approaches to substance misuse prevention.

Deadline: April 17, 2026
Award Amount: Up to $30,000,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments
Description: The Bureau of Reclamation administers the Small Surface and Groundwater Storage Program to support the development of small water storage projects that enhance long-term water availability in the 17 western states, Alaska, and Hawaii. Funded through the Infrastructure Investment and Jobs Act (2021), the program provides up to a 25% federal cost-share for the planning, design, or construction of surface and groundwater storage projects with capacities between 200 and 30,000 acre-feet. The program aims to help communities stretch limited water supplies, reduce conflicts, and improve water reliability by supporting projects that increase storage, improve water management flexibility, and deliver multiple benefits such as groundwater recharge, water quality improvements, and ecosystem health.

Deadline: April 28, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: Tribal Governments, Nonprofits, Higher Education, and Businesses
Description: This grant aims to support projects that enhance the safety, security, and privacy of open-source ecosystems, including tools, methods, or processes that protect open source software from abuse, vulnerabilities, or privacy violations. Awards will fund work such as threat modeling, privacy enhancing technologies, secure tooling, and community governance mechanisms to strengthen open source infrastructure.

Deadline: May 7, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Nonprofits, and Education
Description: This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven.

Deadline: May 8, 2026
Award Amount: $1,000 to $25,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, and Nonprofits
Description: The Native American Graves Protection and Repatriation Act of 1990 authorizes the Secretary of the Interior to make grants to museums, Indian Tribes, and Native Hawaiian organizations for the purposes of assisting in consultation, documentation, and repatriation of Native American human remains, funerary objects, sacred objects, and objects of cultural patrimony (25 U.S.C. 3008). NAGPRA Repatriation grants assist museums, Indian Tribes, and NHOs to defray costs associated with the packaging, transportation, contamination removal, reburial, and/or storage of NAGPRA human remains or cultural items. Project activities may include, but are not limited to: Travel, Transportation, Testing or decontamination, Building containers for transport, Ceremonial materials, or Staff time. See Program Overview for more details on project activities.

Deadline: Open January 1-June 15, 2026
Award Amount: $5,000.00
Match: None
Eligible Entities: State, City, Township, County, or Tribal Governments, Nonprofits, and Arts/Creatives
Description: Applicants must have received an NM Arts Awards in FY25. This grant supports organizations in developing a local, arts-based planning process aimed at improving individual and community well-being through enhanced social connectedness and belonging. The process focuses on engaging underserved populations and preparing organizations for future implementation and funding opportunities.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher, Nonprofits, and Small Businesses
Description: The NSF Division of Environmental Biology (DEB) funds research and training in ecological and evolutionary biology. It supports projects investigating processes at levels from populations and species up to ecosystems and biogeographic scales. Funded work may include field, laboratory, or modeling studies, and interdisciplinary proposals crossing levels of organization or temporal/spatial scales are encouraged.

Deadline: Rolling
Award Amount: 65% discount on eligible broadband connectivity expenses for eligible rural health care providers (HCPs)
Match: None
Eligible Entities: Nonprofits, Higher Education, State, City, Township, County or Tribal Health Department/Agency
Description: The Healthcare Connect Fund (HCF) Program provides a 65% discount on eligible broadband connectivity expenses for eligible rural health care providers (HCPs). You can apply as an individual health care provider or as a consortium, i.e., a group of HCPs that can be both rural and non-rural.

Deadline: Rolling
Award Amount: $15,000 to $25,000
Match: None
Eligible Entities: City, Township, County or Tribal Governments, Fire, and Public Safety
Description: Provides financial, equipment, and training assistance to firefighters, police officers, and EMTs to enhance their safety and effectiveness. It also supports the mental wellness of first responders, offers home modifications for severely wounded personnel, and provides aid to families of fallen heroes. The program’s goal is to ensure first responders and their families have the resources and support they need to serve their communities.

Deadline: Applications accepted as long as funds available.
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits
Description: The RHP supports individuals in recovery on their path to self-sufficiency by providing stable housing and recovery services. Specifically, it funds the development or maintenance of housing and related support for those impacted by substance use disorders.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, and Nonprofits
Description: Supports fundamental, applied, and translational research to advance STEM teaching and learning in both formal (pre-K–12) and informal settings, encouraging innovative, multidisciplinary projects that leverage emerging technologies like AI to develop tools, frameworks, and new insights in STEM education.

Deadline: December 31, 2026
Award Amount: $10,000 to $10,000,000
Match: None
Eligible Entities: Land Grant Institutions, Hispanic Serving Institutions, Nonprofits, and Businesses
Description: The AFRI Foundational and Applied Science Program supports grants in six AFRI priority areas to advance knowledge in both fundamental and applied sciences important to agriculture. The six priority areas are:

Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities.

Deadline: Rolling
Award Amount: $100,000 to $30,000,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments, Nonprofits, Businesses, and Higher Education
Description: Provides funding to support economic development initiatives in distressed communities. These programs aim to enhance infrastructure, promote resilience, and foster job creation through investments in public works and economic adjustment projects. Priority is given to projects that align with EDA’s investment priorities, including equity, workforce development, and environmentally sustainable development.

Deadline: Rolling
Award Amount: $50,000 to $600,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, Nonprofits, and Business
Description: The Cyberinfrastructure for Public Access and Open Science, (CIPAOS) program within the Office of Advanced Cyberinfrastructure (OAC) aims to catalyze new and transformative socio-technical partnerships supporting research data infrastructure ecosystems across domains through early-stage collaborative activities between cyberinfrastructure researchers, scientists, research computing experts, data management experts, research labs, university libraries, and other communities of practice. The CI PAOS program supports the NSF Public Access Initiative by encouraging innovation across the CI ecosystem to address accessibility, discoverability, reliability, reproducibility, sustainability, and utility of data products in alignment with NSF and national goals for public access and open science.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, Nonprofits, and Small Businesses
Description: The Life and Environments Through Time (LET) program supports research that advances knowledge about the patterns and processes relating to the origin and evolution of Earth’s climate, environments, life, and sedimentary record. This research takes place at the molecular, local, regional, and global scales from the Archean Eon through the Holocene epoch. LET-supported research can be useful for predicting and planning for future global change, and for the maintenance and security of ecosystem services and human societies

Deadline: Rolling
Award Amount: Up to $3,000,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education Entities, Nonprofits, and Businesses
Description: The NSF STEM K-12 program in the Division of Research on Learning in Formal and Informal Settings (DRL) in the Directorate for STEM Education (EDU) supports fundamental, applied, and translational research that advances STEM teaching and learning and improves understanding of education across the human lifespan and a range of formal and informal settings.

Deadline: Rolling Monthly
Award Amount: $3,000
Match: None
Eligible Entities: Tribal Governments, Arts/Creatives, and Nonprofits
Description: This opportunity seeks emerging Native American artists (visual, performing & literary artists welcomed). The selected artists must reside at the Amerind Museum for 1 month at a time. The selected artist(s) will receive housing, workspace, and a $3,000/month stipend. The artist will be asked to give a public talk about their work and/or hold some open studio hours. While in residence, the artist can sell their work directly to the public. Depending on the nature of the artist’s work, the Amerind Museum may consider an exhibition or similar event by the selected artist. The artist must have reliable transportation.

Deadline: Rolling
Award Amount: Up to $1,000,000
Match: Not required, but encouraged.
Eligible Entities: City, Township, County or Tribal Governments with populations below 40,000 and Nonprofits
Description: This program helps eligible communities prepare, or recover from, an emergency that threatens the availability of safe, reliable drinking water. Applicants must show that a major decline in quantity or quality of water occurred within two years of the date of the application. Grants are also awarded when a significant decline in quality and quantity of water is imminent. A federal disaster declaration is not required in order to qualify.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: City, Township, County or Tribal Governments and Nonprofits
Description: Those applying must serve an area with a population of 10,000 or less. This program provides technical assistance to rural water systems that are experiencing day-to-day operational, financial or managerial issues. Rural water system officials may request assistance from the National Rural Water Association State Association or the local Rural Utilities Service office. Rural Utilities Service staff may also request assistance on behalf of the system.

Deadline: Rolling
Award Amount: Dependent upon population and median household income.
Match: Dependent upon population and median household income.
Eligible Entities: City, Township, County or Tribal Governments and Nonprofits
Description: Those applying must be a rural area, classified as having no more than 20,000 residents. This program provides affordable funding to develop essential community facilities in rural areas. An essential community facility is defined as a facility that provides an essential service to the local community for the orderly development of the community in a primarily rural area, and does not include private, commercial or business undertakings.

Deadline: Rolling
Award Amount: Up to $250,000
Match: 5% non-federal share.
Eligible Entities: Tribal
Description: This program provides funding to 1994 Land Grant Institutions (Tribal Colleges) to make capital improvements to their educational facilities and to purchase equipment. Funds may be used for infrastructure improvements, to purchase equipment, and to develop essential community facilities. These community facilities include: Schools, education equipment, libraries, dorms, vehicles and major equipment, education and cultural projects, and renovations and improvements.

Deadline: Monthly on the 10th
Award Amount: $100 and $5,000
Match: None
Eligible Entities: Tribal Governments, Film/Media, Arts/Creatives, and Nonprofits
Description: This opportunity supports the growing number of Native artists and culture bearers who need financial assistance with a professional development opportunity or a hardship hindering their creative practice. Applicants must be enrolled members of, or provide proof of lineal descendency from, a U.S. federally recognized or U.S. state-recognized tribe or be able to provide evidence of ancestry as an Alaska Native or Native Hawaiian. This program offers grants between $100 and $5,000.