Deadline: March 5, 2026
Award Amount: Up to $250,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Education, Nonprofits, and Businesses
Description: This funding opportunity focuses on biomedical discovery and data-powered health, integrating streams of complex and interconnected research outputs that can be translated into scientific insights, clinical care, public health practices, and personal wellness to ensure the research is scalable, reproducible, and generalizable.

The scope of NLM’s interest in these research domains is broad, with emphasis on new and innovative methods and approaches to foster data driven discovery in the biomedical and clinical health sciences as well as domain-independent, scalable, and reusable approaches to discovery, curation, analysis, organization, and management of health-related data and digital objects.

Deadline: March 6, 2026
Award Amount: Up to $100,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Education, Nonprofits, and Businesses
Description: The New Investigator Gateway Award in T1D Research is designed to support a robust pipeline of innovative projects and talented new investigators in T1D research. In addition to providing support for preliminary research, the Gateway program provides an opportunity for new Program Directors/Principal Investigators (PD/PIs) to pursue their studies within the intellectual environment of a select number of large, ongoing collaborative research programs.

Deadline: March 16, 2026
Award Amount: Up to $100,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Nonprofits, and Education
Description: This Small Research Grant will support meritorious projects to provide needed scientific insight to improve the prevention, diagnosis, treatment, and/or care for individuals with Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD). Specifically, this NOFO will support projects covering a wide range of topics related to AD/ADRD. The overall goal of this NOFO is (1) to encourage the next generation of researchers to pursue research and academic careers in AD/ADRD research; and (2) to stimulate established researchers who have not had a major award in AD/ADRD research to perform pilot studies to develop new, innovative AD/ADRD research programs that leverage and build upon their existing expertise.

Deadline: April 14, 2026
Award Amount: Up to $125,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits
Description: Supports community-based efforts to prevent and reduce youth substance use, including alcohol, tobacco, and illicit drugs. It provides funding for coalitions that engage multiple sectors, such as schools, law enforcement, and local organizations, to implement evidence-based prevention strategies. The initiative aims to strengthen community capacity and promote sustainable, data-driven approaches to substance misuse prevention.

Deadline: April 17, 2026
Award Amount: Up to $30,000,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments
Description: The Bureau of Reclamation administers the Small Surface and Groundwater Storage Program to support the development of small water storage projects that enhance long-term water availability in the 17 western states, Alaska, and Hawaii. Funded through the Infrastructure Investment and Jobs Act (2021), the program provides up to a 25% federal cost-share for the planning, design, or construction of surface and groundwater storage projects with capacities between 200 and 30,000 acre-feet. The program aims to help communities stretch limited water supplies, reduce conflicts, and improve water reliability by supporting projects that increase storage, improve water management flexibility, and deliver multiple benefits such as groundwater recharge, water quality improvements, and ecosystem health.

Deadline: May 7, 2026
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Businesses, Nonprofits, and Education
Description: This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven.

Deadline: May 8, 2026
Award Amount: $1,000 to $25,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, and Nonprofits
Description: The Native American Graves Protection and Repatriation Act of 1990 authorizes the Secretary of the Interior to make grants to museums, Indian Tribes, and Native Hawaiian organizations for the purposes of assisting in consultation, documentation, and repatriation of Native American human remains, funerary objects, sacred objects, and objects of cultural patrimony (25 U.S.C. 3008). NAGPRA Repatriation grants assist museums, Indian Tribes, and NHOs to defray costs associated with the packaging, transportation, contamination removal, reburial, and/or storage of NAGPRA human remains or cultural items. Project activities may include, but are not limited to: Travel, Transportation, Testing or decontamination, Building containers for transport, Ceremonial materials, or Staff time. See Program Overview for more details on project activities.

Deadline: Open January 1-June 15, 2026
Award Amount: $5,000.00
Match: None
Eligible Entities: State, City, Township, County, or Tribal Governments, Nonprofits, and Arts/Creatives
Description: Applicants must have received an NM Arts Awards in FY25. This grant supports organizations in developing a local, arts-based planning process aimed at improving individual and community well-being through enhanced social connectedness and belonging. The process focuses on engaging underserved populations and preparing organizations for future implementation and funding opportunities.

Deadline: September 30, 2026
Award Amount: Unspecified
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits
Description: The National Park Service American Battlefield Protection Program (NPS ABPP) promotes the preservation, restoration, and interpretation of historic battlefields and associated sites as part of America’s shared heritage. Through the Battlefield Land Acquisition Grants (BLAG), the program helps state and local governments, Tribes, and nonprofits protect eligible Revolutionary War, War of 1812, and Civil War battlefield lands by funding fee-simple or easement acquisitions with a required non-federal match. The program supports community-driven stewardship and ensures public access to preserved lands, with an emphasis on expanding preservation efforts leading up to the nation’s 250th anniversary in 2026.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher, Nonprofits, and Small Businesses
Description: The NSF Division of Environmental Biology (DEB) funds research and training in ecological and evolutionary biology. It supports projects investigating processes at levels from populations and species up to ecosystems and biogeographic scales. Funded work may include field, laboratory, or modeling studies, and interdisciplinary proposals crossing levels of organization or temporal/spatial scales are encouraged.

Deadline: Rolling
Award Amount: 65% discount on eligible broadband connectivity expenses for eligible rural health care providers (HCPs)
Match: None
Eligible Entities: Nonprofits, Higher Education, State, City, Township, County or Tribal Health Department/Agency
Description: The Healthcare Connect Fund (HCF) Program provides a 65% discount on eligible broadband connectivity expenses for eligible rural health care providers (HCPs). You can apply as an individual health care provider or as a consortium, i.e., a group of HCPs that can be both rural and non-rural.

Deadline: Rolling
Award Amount: $15,000 to $25,000
Match: None
Eligible Entities: City, Township, County or Tribal Governments, Fire, and Public Safety
Description: Provides financial, equipment, and training assistance to firefighters, police officers, and EMTs to enhance their safety and effectiveness. It also supports the mental wellness of first responders, offers home modifications for severely wounded personnel, and provides aid to families of fallen heroes. The program’s goal is to ensure first responders and their families have the resources and support they need to serve their communities.

Deadline: Applications accepted as long as funds available.
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits
Description: The RHP supports individuals in recovery on their path to self-sufficiency by providing stable housing and recovery services. Specifically, it funds the development or maintenance of housing and related support for those impacted by substance use disorders.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, and Nonprofits
Description: Supports fundamental, applied, and translational research to advance STEM teaching and learning in both formal (pre-K–12) and informal settings, encouraging innovative, multidisciplinary projects that leverage emerging technologies like AI to develop tools, frameworks, and new insights in STEM education.

Deadline: Rolling
Award Amount: $100,000 to $30,000,000
Match: Yes
Eligible Entities: State, City, Township, County or Tribal Governments, Nonprofits, Businesses, and Higher Education
Description: Provides funding to support economic development initiatives in distressed communities. These programs aim to enhance infrastructure, promote resilience, and foster job creation through investments in public works and economic adjustment projects. Priority is given to projects that align with EDA’s investment priorities, including equity, workforce development, and environmentally sustainable development.

Deadline: Rolling
Award Amount: $50,000 to $600,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, Nonprofits, and Business
Description: The Cyberinfrastructure for Public Access and Open Science, (CIPAOS) program within the Office of Advanced Cyberinfrastructure (OAC) aims to catalyze new and transformative socio-technical partnerships supporting research data infrastructure ecosystems across domains through early-stage collaborative activities between cyberinfrastructure researchers, scientists, research computing experts, data management experts, research labs, university libraries, and other communities of practice. The CI PAOS program supports the NSF Public Access Initiative by encouraging innovation across the CI ecosystem to address accessibility, discoverability, reliability, reproducibility, sustainability, and utility of data products in alignment with NSF and national goals for public access and open science.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education, Nonprofits, and Small Businesses
Description: The Life and Environments Through Time (LET) program supports research that advances knowledge about the patterns and processes relating to the origin and evolution of Earth’s climate, environments, life, and sedimentary record. This research takes place at the molecular, local, regional, and global scales from the Archean Eon through the Holocene epoch. LET-supported research can be useful for predicting and planning for future global change, and for the maintenance and security of ecosystem services and human societies

Deadline: Rolling
Award Amount: Up to $3,000,000
Match: None
Eligible Entities: State, City, Township, County or Tribal Governments, Higher Education Entities, Nonprofits, and Businesses
Description: The NSF STEM K-12 program in the Division of Research on Learning in Formal and Informal Settings (DRL) in the Directorate for STEM Education (EDU) supports fundamental, applied, and translational research that advances STEM teaching and learning and improves understanding of education across the human lifespan and a range of formal and informal settings.

Deadline: Rolling
Award Amount: N/A
Match: None
Eligible Entities: State, City, Township, or County Governments and Nonprofits
Description: The federal personal property donation program enables certain certain non-federal organizations to obtain property the federal government no longer needs. State agencies for surplus property (SASPs) are state-run organizations that administer the federal program for donating federal surplus property to public, tax-supported entities and eligible private nonprofit tax-exempt organizations.

Deadline: Rolling
Award Amount: Up to $1,000,000
Match: Not required, but encouraged.
Eligible Entities: City, Township, County or Tribal Governments with populations below 40,000 and Nonprofits
Description: This program helps eligible communities prepare, or recover from, an emergency that threatens the availability of safe, reliable drinking water. Applicants must show that a major decline in quantity or quality of water occurred within two years of the date of the application. Grants are also awarded when a significant decline in quality and quantity of water is imminent. A federal disaster declaration is not required in order to qualify.

Deadline: Rolling
Award Amount: Unspecified
Match: None
Eligible Entities: City, Township, County or Tribal Governments and Nonprofits
Description: Those applying must serve an area with a population of 10,000 or less. This program provides technical assistance to rural water systems that are experiencing day-to-day operational, financial or managerial issues. Rural water system officials may request assistance from the National Rural Water Association State Association or the local Rural Utilities Service office. Rural Utilities Service staff may also request assistance on behalf of the system.

Deadline: Rolling
Award Amount: Dependent upon population and median household income.
Match: Dependent upon population and median household income.
Eligible Entities: City, Township, County or Tribal Governments and Nonprofits
Description: Those applying must be a rural area, classified as having no more than 20,000 residents. This program provides affordable funding to develop essential community facilities in rural areas. An essential community facility is defined as a facility that provides an essential service to the local community for the orderly development of the community in a primarily rural area, and does not include private, commercial or business undertakings.

Deadline: Rolling
Award Amount: Dependent upon project.
Match: None
Eligible Entities: Nonprofits, Community Water Systems
Description: With the increase in demand and federal requirements for the DWSRF, The State of New Mexico will continue to choose the projects to fulfill the federal equivalency requirements. Additionally, the schedule by which the priority lists will be published will remain semi‐annual. Lists are produced in December and May with supplemental lists published in September and February if project interest and urgency exist. Criteria for project interest and urgency are included in this IUP to clarify when the supplemental lists will be produced. Project priority ranking criteria for emerging contaminants were updated to reflect increased value on providing water service to underserved communities or where wells are contaminated by emerging contaminants.

Deadline: Rolling
Award Amount: Dependent upon project.
Match: Dependent upon project.
Eligible Entities: State, City, Township, County or Tribal Governments and Nonprofits.
Description:  A brownfield is a property whose redevelopment is complicated by the presence of contamination or perceived contamination. Examples include old gas stations, vacant motels, former industrial sites or abandoned dumps. Cleaning up and reinvesting in these properties can restore the environment, reduce health risks, eliminate blight, revitalize downtowns, create jobs, increase local tax bases, and create a sense of community pride.

NMED offers free environmental evaluations of brownfield properties. Services include: Phase I & II environmental site assessments; Environmental investigations (sampling and analysis); Asbestos and lead paint surveys: Clean-up planning: and Remediation cost estimates. NMED also offers the Brownfield Clean-Up Revolving Loan Fund.

Deadline: July 17, 2029
Award Amount: Up to $10,000 for a project period not to exceed 2 years
Eligible Entities: Higher Education Institutions, Nonprofits, Governments, including Tribal, ISDs, Housing Authorities.
Description: The Agency for Healthcare Research and Quality (AHRQ) Small Research Grant Program supports different types of health services research projects, including: Pilot and feasibility studies, secondary analysis of existing data, small, self-contained research projects, development of research methodology, and development of new research technology.

Deadline: Ongoing
Award Amount: Up to $50,000
Eligible Entities: Local Governments, including tribal entities and mutual domestic water consumers associations
Description: The Local Government Planning Fund funds critical planning documents for a variety of public infrastructure projects. Eligible plans include Preliminary Engineering Reports, Feasibility Studies, Environmental Information Documents, Comprehensive Plans, Asset Management Plans, Water Conservation Plans, Master Plans, Local Economic Development Act Plans and Metropolitan Redevelopment Act Plans. Applications are accepted monthly and grants are made on a reimbursement basis.

Deadline: Ongoing
Amount: Loans of up to 30 years at a fixed, below-market interest rates 
Eligible Entities: Municipal and Community Water Systems
Description: For water projects that are shovel ready, local government agencies can access to millions of dollars in low interest loans and even get some grant funding depending on median household income levels.

Description: AEFLA seeks to create a partnership between states, the Federal government, and local adult education providers to help adults get the basic skills they need including reading, writing, math, English language proficiency, and problem-solving to be productive workers, family members, and citizens.

Deadline: Rolling
Award Amount: $75 million appropriation
Eligible Entities: State, City, Township, County or Tribal Governments
​Description: DFA offers three grant programs providing eligible entities with a reliable and nimble source of funding to increase competitiveness for hundreds of federal grant program opportunities that require local match.
​
​Matching Grant – for eligible entities that require additional funding to meet the minimum match requirement for a federal grant (at least 40% of available funds are reserved for rural, frontier, and tribal governments).

Project Implementation Grant – for recipients of a Matching Grant that require capacity funding to fully implement the federally funded project associated with the Matching Grant.
(Only available if awarded a Matching Grant)

Apply for Federal Compliance Offset Grant – for eligible entities that demonstrate higher project costs due to compliance with federal funding requirements, such as requirements related to worker wages and sourcing American-made materials.